Gladiator is a science fiction novel by American author Philip Wylie, first published in 1930. The story concerns a scientist who invents an "alkaline free-radical" serum to "improve" humankind by granting the proportionate strength of an ant and the leaping ability of the grasshopper. The scientist injects his pregnant wife with the serum and his son Hugo Danner is born with superhuman strength, speed, and bulletproof skin. Hugo spends much of the novel hiding his powers, rarely getting a chance to openly use them.

The novel is widely assumed to have been an inspiration for Superman due to similarities between Danner and the earliest versions of Superman who debuted in 1938, though no confirmation exists that Superman creators Jerry Siegel and Joe Shuster were directly influenced by Wylie's work.

The story begins at the turn of the 20th century. Professor Abednego Danner lives in a small, rural Colorado town, and has a somewhat unhappy marriage to a conservative religious woman. Obsessed with unlocking genetic potential, Danner experiments with a tadpole (which breaks through the bowl he's keeping it in), and a pregnant cat, whose kitten displays incredible strength and speed, managing to maul larger animals. Fearing the cat may be uncontrollable, Danner poisons it. When his wife becomes pregnant with their first child, Danner duplicates his experiment on his unknowing wife.

Their child Hugo almost immediately displays incredible strength, and Danner's wife realizes what her husband has done. Though she hates him, she does not leave him, and they instead raise their son to be respectful of his incredible gift and sternly instruct him never to fight, or otherwise reveal his gifts, lest he be the target of a witch-hunt. Hugo grows up being bullied at school, unwilling to fight back. However, he finds release when he discovers the freedom the wilderness around his hometown provides, unleashing his great strength on trees as a manner of playing.

Hugo finds success in his teenage years, becoming a star football player, and receives a college scholarship. He spends summers and free time trying to find uses for his strength, becoming a professional fighter and strongman at a boardwalk. After killing another player during a football game, Hugo quits school.